Gumboro

Does the Lohmann range cover all needs of the Gumboro live vaccine market?

Yes, Lohmann Animal Health provides its customers with a complete range of Gumboro live vaccines. Available are live vaccines from mild up to intermediate plus.

You find in our portfolio the mild vaccine AviPro VIBURSA L, the intermediate vaccines AviPro VIBURSA CE, AviPro GUMBORO VAC and AviPro PRECISE as well as the intermediate plus vaccine AviPro IBD XTREME. This covers all contingencies that might be requested from a Gumboro live vaccination programme.

What is the difference between mild, intermediate, intermediate plus and hot?

Live IBD vaccines can be categorised by their breakthrough titre, virulence and potential to induce immune suppression. According to these factors they are divided into mild, intermediate and intermediate plus (or hot) vaccines.

While the mild IBD vaccines show the lowest invasiveness and therefore are used mainly for day-of-age vaccination in chicks with low or no MDAs (Maternally Derived Antibodies), the intermediate plus vaccines have the highest virulence, breakthrough titre and potential to induce immune suppression. The intermediate vaccines stand between these two groups and are used under “normal” conditions as a standard procedure applying for most situations in the field.

The term “hot” is misleadingly often perceived as referring to vaccines hotter than intermediate plus, but in fact, when this term is used for vaccines, it relates to the same category of invasiveness and virulence as the term intermediate plus does.

What is the advantage of using intermediate plus vaccines?

Young chicks are protected against a field challenge of IBDV by MDAs. But the level of this maternal immunity decreases with time and the chicks become more and more susceptible to the virus. The MDA level not only protects against the field challenge, but it also neutralises live IBD vaccines when they are given too early. The capability of a vaccine to take in a chick depends on its breakthrough titre. The higher the titre is, the earlier can it break through the maternal immunity. Intermediate plus vaccines have the highest breakthrough titre and can therefore break earlier through the maternal immunity than mild or intermediate vaccines could do.

In case of vvIBD (very virulent IBD), due to its virulence, the virus is able to break through relatively high levels of MDAs. Intermediate plus vaccines enable us to vaccinate the chickens before the vvIBDV field strains infect them.

Does Lohmann provide a general programme on Gumboro vaccination that would work under most conditions worldwide?

Lohmann supplies its customers with a recommended vaccination programme for each of their vaccines.  But we have to keep in mind that an ideal and successful vaccination programme should be “tailor made” for each flock, because to be effective a Gumboro vaccine has to be given at the right time. The correct time of vaccination depends primarily on the level of maternally derived antibodies in the chicks and the breakthrough titre of the vaccine on the one hand, as well as on the virulence of the field virus and the infection pressure on the other hand. A right time for one vaccine might be too early for another with a lower breakthrough titre.

The identification of the correct time of vaccination can be done in many different ways: by serology, meaning the analysis of blood samples, by estimation, which requires the knowledge of the parents’ vaccination schedule or just by several vaccinations at different times in order to be sure to protect birds with different MDA levels.

Some companies seem to favour a multiple live vaccination programme for Gumboro. What is the difference? The vaccines are not sufficiently good?

The principles of maternal protection, level of field challenge and vaccine breakthrough titre are applicable to all geographical and epidemiological situations. So are the vaccines efficacious when given at the right time. The multiple live vaccination programmes are designed under the third approach mentioned above, which is to ensure that birds with any different levels of MDA are protected at the right moment. This methodology is efficacious and covers any gaps in protection from flocks with uneven levels of MDA. 



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